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Screening for Heart Disease

Screening ECGs (either at rest or with exercise) are not recommended in those without symptoms who are at low risk. This includes those who are young without risk factors. In those at higher risk the evidence for screening with ECGs is inconclusive.

Some biomarkers may add to conventional cardiovascular risk factors in predicting the risk of future cardiovascular disease; however, the clinical value of some biomarkers is still questionable.

Currently, biomarkers that may reflect a higher risk of cardiovascular disease include the following

  • Carotid intima-media thickness

  • Carotid total plaque area

  • Higher fibrinogen and PAI-1 blood concentrations

  • Elevated homocysteine

  • Elevated blood levels of asymmetric dimethylarginine

  • Inflammation as measured by C-reactive protein

  • Elevated Low-density lipoprotein-p

  • Elevated blood levels of brain natriuretic peptide (also known as B-type) (BNP)