Advanced Cholesterol Testing

The VAP (vertical auto profile) test is a cholesterol, lipid and lipoprotein test. The name "VAP test" was coined by the privately held cardio-diagnostic company Atherotech to identify their direct-measurement method, which categorizes not just total cholesterol, high-density lipoproteins (HDL), and low-density lipoproteins (LDL), but all lipids and subclasses, with an LDL measurement accuracy unaffected by triglycerides.

Atherotech claims their VAP test has a unique ability to identify far more areas of risk to patients than the standard lipid panel, specifically because it reports 15 separate components versus four in the standard cholesterol test. Their study reported that the more comprehensive test was able to identify more than twice the number of patients with lipid abnormalities than the standard lipid panel (cholesterol and triglyceride test).

The VAP test directly measures LDL, including the LDL particle size pattern. It also measures very low density lipoprotein (VLDL), intermediate-density lipoprotein (IDL) and lipoprotein(a).

The test was intended to meet the American Diabetes Association and American College of Cardiology (ADA-ACC) cholesterol guidelines for people at high risk of heart attack and stroke (including people with Type 2 diabetes mellitus). The ADA-ACC consensus statement establishes measurement and treatment guidelines for apoB in addition to LDL and non-HDL in high-risk patients. The VAP test was the first cholesterol profile to comply with updated National Cholesterol Education Program ATP III recommendations for LDL measurement.